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Norovirus candidate vaccine induces broad antibody responses in trial...

A multivalent candidate vaccine elicits broad antibody responses to a range of norovirus strains, including strains not included in the vaccine or previously encountered by participants, according to a...

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Ebola whole virus vaccine shown effective, safe in primates

An Ebola whole virus vaccine, constructed using a novel experimental platform, has been shown to effectively protect monkeys exposed to the often fatal virus.

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Paracetamol is ineffective for lower back pain

Paracetamol is not effective in the treatment of spinal pain and provides negligible benefits for osteoarthritis, according to a study published in The BMJ today.

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New study reveals mixed picture on the effectiveness of Viagra and related drugs

Viagra and other related drugs are not a universal 'cure-all' for impotence, according to a new study from The University of Manchester and NatCen Social Research.

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Cost of cancer drugs varies widely based on who's paying

Uninsured cancer patients are asked to pay anywhere from two to 43 times what Medicare would pay for chemotherapy drugs, according to a new study from the University of North Carolina at Chapel Hill.

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European watchdog seeks tighter guidelines on ibuprofen

A European panel on Monday backed tougher guidelines on ibuprofen after research found high doses of the popular painkiller were linked to a small increase in cardiac and stroke risk.

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Your pain reliever may also be diminishing your joy

Researchers studying the commonly used pain reliever acetaminophen found it has a previously unknown side effect: It blunts positive emotions.

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Certain genes might make some people more prone to experience the placebo effect

Placebos have helped to ease symptoms of illness for centuries and have been a fundamental component of clinical research to test new drug therapies for more than 70 years. But why some people respond...

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Cellular signals for pain fine tune neurons' sensitivity to opiods

At the cellular level, pain and pain relief are caused by two different signaling pathways. But the two pathways aren't necessarily independent of one another, according to a study published by...

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New gel medication breakthrough delays release of drug to benefit the patient

Scientists at the University of Huddersfield are pioneering the use of a special gel that is ideal for administering medication to young children and others - including the elderly - who have...

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Drug prices to treat multiple sclerosis soar, point to larger problem

A new study released today found that drugs used to treat multiple sclerosis have soared in price in the past two decades, in some cases more than 700 percent, even though newer drugs have come to the...

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Microneedle patch for measles vaccination could be a global game changer

A new microneedle patch being developed by the Georgia Institute of Technology and the Centers for Disease Control and Prevention (CDC) could make it easier to vaccinate people against measles and...

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Generic transplant drugs as good as brand name, study finds

A University of Cincinnati (UC)-led research team has found that generic formulations of tacrolimus, a drug used post-transplant to lower the risk of organ rejection, are just as good as the name-brand...

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Does publication bias make antidepressants seem more effective at treating...

In scientific literature, studies with "good" results are more likely to be published than studies with results that are unclear or negative. A study with a new, exciting finding (a positive result) is...

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Researcher develops bird flu vaccine using virus commonly found in dogs

Researchers at the University of Georgia have used a virus commonly found in dogs as the foundation for a new vaccine against H7N9 influenza, more commonly known as bird flu.

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'Imperfect drug penetration' speeds pathogens' resistance, study finds

Prescribing patients two or more drugs that do not reach the same parts of the body could accelerate a pathogen's resistance to all of the drugs being used in treatment, according to a new study...

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Paracetamol in pregnancy may lower testosterone in unborn boys

Prolonged paracetamol use by pregnant women may reduce testosterone production in unborn baby boys, research has found.

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Re-engineered antibiotic shows potential for treatment of drug-resistant...

Researchers led by St. Jude Children's Research Hospital scientists have developed a second-generation antibiotic that shows early effectiveness against common bacterial infections that pose a serious...

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New evidence confirms link between newer contraceptive pills and higher clot...

A study published by The BMJ today provides new evidence to confirm the link between newer contraceptive pills and higher risk of serious blood clots (known as venous thromboembolism or VTE).

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Newer, easier to manage medications may not always be the best choice

If you are over age 75, and taking an anticoagulant, the old standard may be the gold standard, Mayo Clinic researchers and collaborators have determined.

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Available genetic data could help doctors prescribe more effective...

There is a wealth of published information describing interactions between drugs used to treat cardiovascular disease and the genetic variations that can affect how patients respond to them. But few...

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Concerns remain for 'Viagra for women' twice rejected by FDA

The makers of a pill intended to boost sexual desire in women will try again this week to persuade regulators that the drug warrants approval after two rejections.

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FDA panel backs female libido pill, under safety conditions

The drug industry's decade-spanning search for a female equivalent to Viagra took a major step forward Thursday, as government experts recommended approval for a pill to boost sexual desire in women.

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FDA panel backs first-in-class cholesterol drug

Federal health advisers on Tuesday recommended approval for a highly-anticipated cholesterol drug from Sanofi and Regeneron Pharmaceuticals, but with the caveat that more data is needed about its...

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Study shows first signs that drug used to treat ADHD may improve cognitive...

According to a new study, women experiencing difficulty with time management, attention, organization, memory, and problem solving - often referred to as executive functions - related to menopause may...

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Model could help counteract poisoning from popular painkiller

New research could help reverse deadly side effects caused by excessive doses of the drug acetaminophen, the major ingredient in Tylenol and many other over-the-counter and prescription medicines.

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Drug may be antidote to bleeding tied to blood thinner pradaxa

(HealthDay)—The new blood thinner Pradaxa (dabigatran) is being widely used, but it comes with one serious drawback: rare but dangerous cases of sudden, uncontrolled bleeding in patients.

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National study finds life-threatening barriers in access to breakthrough drugs

Most states violate federal Medicaid law because they deny coverage for sofosbuvir, a new and highly effective treatment to cure hepatitis C, according to Lynn E. Taylor, M.D., director of The Miriam...

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Statins linked to lower aggression in men, but higher in women

Statins are a hugely popular drug class used to manage blood cholesterol levels and reduce the risk of heart disease. Previous studies had raised questions about adverse behavioral changes with...

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One in four people prescribed opioids progressed to longer-term prescriptions

Opioid painkiller addiction and accidental overdoses have become far too common across the United States. To try to identify who is most at risk, Mayo Clinic researchers studied how many patients...

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